COOPER W G, REGER J F, VAN BREEMEN V L
J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):283-6. doi: 10.1083/jcb.2.4.283.
Basement membranes in the kidney are made up of a homogeneous matrix. In argyria, silver passes from the blood in the ionic form and diffuses into the kidney basement membranes in which it is precipitated. X-ray diffraction studies of "silver-stained" rat kidneys show that most of the silver in the kidneys is combined with some form of sulfur. Histochemical staining for sulfhydryls and disulfides demonstrates the presence of these groups in basement membranes. It appears that silver ions combine with either or both the sulfhydryl or disulfide groups in the basement membranes and also in mitochondria (when the silver diffuses into a cell).
肾脏中的基底膜由均质基质组成。在银质沉着病中，银以离子形式从血液中进入并扩散到肾脏基底膜中，在那里沉淀下来。对“银染”大鼠肾脏进行的X射线衍射研究表明，肾脏中的大部分银与某种形式的硫结合。巯基和二硫键的组织化学染色显示这些基团存在于基底膜中。似乎银离子与基底膜以及线粒体中的巯基或二硫键之一或两者结合（当银扩散到细胞中时）。
