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可卡因和甲基苯丙胺依赖多模式住院治疗后的一年随访。

One-year follow-up after multimodal inpatient treatment for cocaine and methamphetamine dependencies.

作者信息

Frawley P J, Smith J W

机构信息

Schick Shadel Hospital of Santa Barbara, California.

出版信息

J Subst Abuse Treat. 1992 Fall;9(4):271-86. doi: 10.1016/0740-5472(92)90020-o.

Abstract

Of a randomly selected sample of 214 patients treated with aversion therapy for cocaine dependence in four chemical dependency units operated by Schick Shadel Hospitals, 156 were followed up 12 to 20 months posttreatment (average 15.2 months). Significant other validation was obtained in 33%. Total abstinence from cocaine for the group overall was 53% at one year post treatment, and current abstinence of at least 6 months at follow-up was 68.6%. Those treating with aversion for cocaine alone had a one-year abstinence of 39% and a current abstinence of 62.4%. Those treating with aversion for alcohol and cocaine had a one-year total abstinence from cocaine of 69% and a current abstinence of 76%. Those treating with aversion for cocaine and marijuana had a one-year total abstinence from cocaine of 50% and a current abstinence of 65%. Those treating with aversion for alcohol, cocaine, and marijuana had a one-year total abstinence from cocaine of 73% and a current abstinence of 73%. One-year total abstinence from alcohol was 54% for those receiving aversion for both alcohol and cocaine and 77% for those receiving aversion for alcohol, cocaine, and marijuana. Current abstinence from alcohol at follow-up was 68% and 81%, respectively. One-year total abstinence from marijuana was 42% for those treating with aversion for cocaine and marijuana and 64% for those treating with aversion for alcohol, cocaine, and marijuana. Current abstinence at follow-up from marijuana was 61% and 81%, respectively. The use of aversion therapy for both alcohol and cocaine in alcoholics who were also using cocaine was associated with higher total abstinence rates (88% vs. 55%) from cocaine when compared with alcoholics who used cocaine but received no aversion as part of their program. The conclusion is tentative since the follow-up rate in this study was lower than that of the previous study (64% vs. 84%). Being around other users accounted for 49% of relapse situations. Family/Work stress was associated with relapse in 33% of cases and unpleasant feelings in 24% of cases. The use of both reinforcement treatments and the use of support following treatment were associated with improved abstinence rates from cocaine. Those patients who reported losing all urges for cocaine after treatment had a total abstinence from cocaine of 90%, those who reported losing all the uncontrollable urges had a total abstinence of 64%, and those who reported still having the urge reported only 33% total abstinence from cocaine.

摘要

在由希克·沙德尔医院运营的四个戒毒治疗中心,对214名接受可卡因依赖厌恶疗法治疗的患者进行随机抽样,其中156人在治疗后12至20个月(平均15.2个月)接受了随访。33%的患者获得了重要他人的证实。该组总体在治疗后一年可卡因完全戒除率为53%,随访时目前至少戒除6个月的比例为68.6%。仅接受可卡因厌恶疗法治疗的患者一年戒除率为39%,目前戒除率为62.4%。接受酒精和可卡因厌恶疗法治疗的患者一年可卡因完全戒除率为69%,目前戒除率为76%。接受可卡因和大麻厌恶疗法治疗的患者一年可卡因完全戒除率为50%,目前戒除率为65%。接受酒精、可卡因和大麻厌恶疗法治疗的患者一年可卡因完全戒除率为73%,目前戒除率为73%。接受酒精和可卡因厌恶疗法治疗的患者一年酒精完全戒除率为54%,接受酒精、可卡因和大麻厌恶疗法治疗的患者为77%。随访时目前酒精戒除率分别为68%和81%。接受可卡因和大麻厌恶疗法治疗的患者一年大麻完全戒除率为42%,接受酒精、可卡因和大麻厌恶疗法治疗的患者为64%。随访时目前大麻戒除率分别为61%和81%。与使用可卡因但未接受厌恶疗法的酗酒者相比,同时使用可卡因的酗酒者接受酒精和可卡因厌恶疗法与更高的可卡因完全戒除率(88%对55%)相关。由于本研究的随访率低于先前研究(64%对84%),因此该结论具有不确定性。与其他使用者接触占复吸情况的49%。家庭/工作压力在33%的病例中与复吸有关,不愉快情绪在24%的病例中与复吸有关。强化治疗和治疗后使用支持与可卡因戒除率提高有关。那些报告治疗后失去对可卡因所有渴望的患者可卡因完全戒除率为9%,那些报告失去所有无法控制的渴望的患者完全戒除率为64%,而那些报告仍有渴望的患者可卡因完全戒除率仅为33%。

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