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在一个包括厌恶疗法和硫喷妥钠访谈的多模式住院项目中接受治疗的600名化学物质依赖患者的治疗结果。

Treatment outcome of 600 chemically dependent patients treated in a multimodal inpatient program including aversion therapy and pentothal interviews.

作者信息

Smith J W, Frawley P J

机构信息

Schick Shadel Hospital of Seattle, WA 98146.

出版信息

J Subst Abuse Treat. 1993 Jul-Aug;10(4):359-69. doi: 10.1016/0740-5472(93)90021-s.

Abstract

A sample of 600 patients treated in a multimodal treatment program using aversion therapy and narcotherapy at three Schick freestanding addiction treatment hospitals and one Schick unit in a general hospital were followed-up. Contact was made a minimum of 12 months and as many as 20 months after completion of treatment (mean 14.7 mos.). Telephone contact was made by an independent research organization with 427 of the patients (71.2%). Of these, 65.1% were totally abstinent for 1 year after treatment and 60.2% were abstinent until follow-up a mean of 14.7 months later. Fifty-two percent of the alcoholics were using or dependent on other drugs at admission. Seventy-five of these treated for cocaine dependence and 47 treated for marijuana dependence. The cocaine 12 month and "total" abstinence (mean 14.7 mos.) rates for the 49 contacted patients were 83.7% and 81.6%, respectively. The marijuana 12 month and "total" abstinence (mean 14.7 mos.) rates for the 30 contacted patients was 70.0% for both groups. Abstinence rates for alcohol and/or other drugs were also calculated including noncontacted patients who had chart documented evidence of relapse. The most powerful predictor of success was whether or not all urges to drink or use had been eliminated (presumably by aversion therapy). Of additional importance was the use of support groups and reinforcement treatments after completion of the initial hospitalization. The two most prominent factors initiating a relapse were "intrapersonal determinants" such as stress from work or marriage/family relationships and "interpersonal determinants" such as being around others who were drinking/using or being at a celebration or special event. The two factors were of equal importance in the alcoholics. However, interpersonal determinants were far more important in the cocaine and marijuana treated patients. Increased utilization of reinforcement treatments was associated with decreased urges to drink/use and increased abstinence rates. In contrast, increased frequency of support group utilization was associated with increased urges to drink/use and lower abstinence rates. This suggests the need to take seriously patient reports of "urges" in the first year after treatment and to carefully assess the cause and initiate or update an individualized plan of treatment. Such treatment may include increased reinforcement treatments, treatment of depression, and additional assistance in coping with intrapersonal and interpersonal determinants of relapse.

摘要

对在三家希克独立成瘾治疗医院和一家综合医院的希克科室接受多模式治疗项目(采用厌恶疗法和麻醉疗法)的600名患者进行了随访。在治疗结束后至少12个月、多达20个月(平均14.7个月)进行了联系。由一个独立研究机构通过电话联系了427名患者(71.2%)。其中,65.1%在治疗后1年完全戒酒,60.2%在平均14.7个月后的随访时仍保持戒酒状态。52%的酗酒者在入院时使用或依赖其他药物。其中75人接受了可卡因依赖治疗,47人接受了大麻依赖治疗。49名接受联系的可卡因依赖患者的12个月及“总体”(平均14.7个月)戒酒率分别为83.7%和81.6%。30名接受联系的大麻依赖患者的12个月及“总体”(平均14.7个月)戒酒率在两组中均为70.0%。还计算了酒精和/或其他药物的戒酒率,包括有病历记录证明复发的未联系患者。成功的最有力预测因素是饮酒或使用药物的冲动是否全部消除(大概是通过厌恶疗法)。另外重要的是在初次住院结束后使用支持小组和强化治疗。引发复发的两个最突出因素是“个人内在决定因素”,如工作压力或婚姻/家庭关系压力,以及“人际决定因素”,如身边有饮酒/使用药物的人或处于庆祝活动或特殊场合。这两个因素在酗酒者中同等重要。然而,人际决定因素在接受可卡因和大麻治疗的患者中更为重要。强化治疗使用的增加与饮酒/使用药物冲动的减少及戒酒率的提高相关。相反,支持小组使用频率的增加与饮酒/使用药物冲动增加及戒酒率降低相关。这表明有必要认真对待治疗后第一年患者关于“冲动”的报告,并仔细评估原因,启动或更新个性化治疗计划。这种治疗可能包括增加强化治疗、治疗抑郁症,以及在应对复发的个人内在和人际决定因素方面提供额外帮助。

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