Siltanen P, Tuuteri L, Norio R, Tala P, Ahrenberg P, Halonen P I
Am J Cardiol. 1976 Aug;38(2):252-6. doi: 10.1016/0002-9149(76)90158-2.
A family is described in which the mother and three of seven children had atrial myxoma. The mother had biatrial myxoma; surgical treatment resulted in massive intraoperative embolization and death. Surgery was sucessful in two sons with left atrial myxoma and systemic arterial embolization. A third son had calcified right atrial myxoma with destruction of the tricuspid valve and episodes of syncope and pulmonary embolism; surgery including valve replacement, was successful. The mother's father and a brother had died suddenly without a definite diagnosis. The family data are consistent with dominant transmission. The possibility of finding affected relatives should be borne in mind when studying patients with atrial myxoma.
本文描述了一个家族，其中母亲和七个孩子中的三个患有心房黏液瘤。母亲患有双房黏液瘤；手术治疗导致术中大量栓塞并死亡。两名患有左房黏液瘤和体循环动脉栓塞的儿子手术成功。第三个儿子患有钙化的右房黏液瘤，伴有三尖瓣破坏、晕厥发作和肺栓塞；包括瓣膜置换在内的手术很成功。母亲的父亲和一个兄弟突然去世，未明确诊断。家族数据符合显性遗传。在研究心房黏液瘤患者时，应考虑到发现患病亲属的可能性。
