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[脊椎动物视网膜色素上皮的髓样小体]

[Myeloid bodies of the retinal pigment epithelium in vertebrates].

作者信息

Nguyen-Legros J

出版信息

Arch Ophtalmol Rev Gen Ophtalmol. 1975 Oct;35(10):759-84.

PMID:133658
Abstract

After the hypothesis of Porter and Yamada about the photoreceptive role of myeloid bodies of the vertebrate pigment epithelium, we have pointed out the fine ultrastructure of these organelles: they consist of piles of flattened saccules, with a lipidic content, and linked together by an inter-saccular cement. They are not like Golgi bodies: they do not content glycoprotein. They must be discarded from phagosomes, which are membrane-bounded and content acid phosphatase activity. An oxido-reductive activity cannot been demonstrated at their level, similar to that observed on the rod outer segments. Freeze-etching does not show peculair organization on their fracture faces. They represent a special organization of the endoplasmic reticulum which seems to have a function in the metabolism of visual pigments in certain species of animals, the retina of which is avascular.

摘要

在波特和山田提出关于脊椎动物色素上皮细胞髓样小体的光感受作用的假说之后,我们指出了这些细胞器的精细超微结构:它们由一堆堆扁平的囊泡组成,含有脂质成分,并通过囊泡间的胶状物连接在一起。它们与高尔基体不同:它们不含糖蛋白。它们必须从吞噬体中被清除,吞噬体是有膜包被的且含有酸性磷酸酶活性。在它们这个水平上无法证明有类似在视杆外段观察到的氧化还原活性。冷冻蚀刻在它们的断裂面上没有显示出特殊的组织结构。它们代表了内质网的一种特殊结构,在某些动物物种的视觉色素代谢中似乎具有功能,这些动物的视网膜是无血管的。

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