介导猫颈背运动神经元双突触兴奋的下行通路：易化性相互作用

Descending pathways mediating disynaptic excitation of dorsal neck motoneurones in the cat: facilitatory interactions.

作者信息

Alstermark B, Pinter M J, Sasaki S

机构信息

Department of Physiology, University of Göteborg, Sweden.

出版信息

Neurosci Res. 1992 Oct;15(1-2):32-41. doi: 10.1016/0168-0102(92)90015-5.

DOI:10.1016/0168-0102(92)90015-5

PMID:1336583

Abstract

Facilitatory interactions between disynaptic EPSPs evoked from the contralateral tectum, ipsilateral tegmentum and contra- and/or ipsilateral pyramid have been investigated in dorsal neck motoneurones of the cat. Monosynaptic convergence on common intercalated neurones was found from ipsi- and contralateral pyramidal, contralateral tectal and ipsilateral tegmental fibres. In addition, disynaptic facilitation was observed from ipsilateral pyramidal fibres on disynaptic contralateral pyramidal EPSPs. Transection of cortico-fugal fibres in the pyramid showed that the location of the interactions occurred in the lower brain stem, suggesting that reticulospinal neurones are mediating the effects.

摘要

在猫的颈背运动神经元中，研究了由对侧顶盖、同侧被盖以及对侧和/或同侧锥体诱发的双突触兴奋性突触后电位（EPSPs）之间的易化性相互作用。发现同侧和对侧锥体、对侧顶盖及同侧被盖纤维对共同的中间神经元存在单突触汇聚。此外，观察到同侧锥体纤维对双突触对侧锥体EPSPs有双突触易化作用。切断锥体中的皮质离心纤维表明，相互作用发生在脑桥下部，提示网状脊髓神经元介导了这些效应。