Pena M J, Elcuaz R, Suárez J, Lafarga B
Unidad de Microbiología, Hospital Nuestra Señora del Pino, Las Palmas de Gran Canaria.
Enferm Infecc Microbiol Clin. 1992 Oct;10(8):481-5.
The 40/41 adenovirus plays an important role as the productive agent of gastroenteritis at a pediatric age according to recent studies. With the aim of evaluating the clinical-epidemiological importance of this agent in our medium a prospective study of the 40/41 adenovirus was carried out in 1,697 stools of children of under 14 years of age over a period of 2 years. An enzyme immunoassay technique with specific monoclonal antibodies was used for detection. The 40/41 adenovirus was the third cause of gastroenteritis following Salmonella sp. and rotavirus with a percentage of infection of 2.1%. In 87.1% of the patients in which it was detected the patients had an age of less than 24 months. A clear peak of infection was found in the months of September of the two years studied. The infection was of intrahospital origin in 46.2% of the patients. Most of the children presented a self-limited diarrheic picture. The evolution of the patients was good with adequate rehydration measures. The study of the 40/41 adenovirus is of indubitable interest with the aim of obtaining greater knowledge of its importance in the epidemiology and clinical manifestations of gastroenteritis.
根据最近的研究，40/41型腺病毒作为小儿肠胃炎的致病原起着重要作用。为了评估该病原体在我们地区的临床流行病学重要性，在两年时间里对1697名14岁以下儿童的粪便进行了一项关于40/41型腺病毒的前瞻性研究。采用了一种使用特异性单克隆抗体的酶免疫测定技术进行检测。40/41型腺病毒是继沙门氏菌属和轮状病毒之后肠胃炎的第三大病因，感染率为2.1%。在检测出该病毒的患者中，87.1%的患者年龄小于24个月。在所研究的两年中的9月份发现了一个明显的感染高峰。46.2%的患者感染源自医院内部。大多数儿童呈现自限性腹泻症状。通过适当的补液措施，患者病情转归良好。对40/41型腺病毒的研究对于更深入了解其在肠胃炎流行病学和临床表现中的重要性无疑具有重要意义。
