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The balance between excitation and inhibition in dentate granule cells and its role in epilepsy.

作者信息

Mody I, Otis T S, Staley K J, Köhr G

机构信息

Department of Neurology and Neurological Sciences M016, Stanford University School of Medicine, CA 94305.

出版信息

Epilepsy Res Suppl. 1992;9:331-9.

PMID:1337447
Abstract
摘要

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The balance between excitation and inhibition in dentate granule cells and its role in epilepsy.齿状颗粒细胞中兴奋与抑制之间的平衡及其在癫痫中的作用。
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GABAergic synapses in hippocampus exocytose aspartate on to NMDA receptors: quantitative immunogold evidence for co-transmission.海马体中的γ-氨基丁酸能突触向N-甲基-D-天冬氨酸受体胞吐天冬氨酸:共传递的定量免疫金证据
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Interplay of Entorhinal Input and Local Inhibitory Network in the Hippocampus at the Origin of Slow Inhibition in Granule Cells.内嗅皮层输入与局部抑制性神经网络在颗粒细胞慢抑制起源的海马体中的相互作用。
J Neurosci. 2019 Aug 14;39(33):6399-6413. doi: 10.1523/JNEUROSCI.2976-18.2019. Epub 2019 Jun 10.
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Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential.稳态还是离子通道病?颞叶癫痫中获得性细胞类型特异性离子通道变化及其抗癫痫潜力。
Front Physiol. 2015 Jun 15;6:168. doi: 10.3389/fphys.2015.00168. eCollection 2015.
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Global optogenetic activation of inhibitory interneurons during epileptiform activity.
在癫痫样活动期间对抑制性中间神经元进行全局光遗传学激活。
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J Neurosci. 2012 Feb 8;32(6):1989-2001. doi: 10.1523/JNEUROSCI.2720-11.2012.
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Neurogliaform cells in the molecular layer of the dentate gyrus as feed-forward γ-aminobutyric acidergic modulators of entorhinal-hippocampal interplay.齿状回分子层中的神经胶质细胞作为额颞叶-海马相互作用的前馈γ-氨基丁酸能调制器。
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Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors.癫痫发作迅速导致海马齿状颗粒细胞GABAA受体对苯二氮䓬和锌离子的敏感性降低。
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