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[豚鼠输尿管收缩功能的肾上腺素能受体调节]

[The adrenoreceptor regulation of ureteral contractile function in the guinea pig].

作者信息

Prokopenko R A, Mohylevych S Ie

出版信息

Fiziol Zh (1978). 1992 Jul-Aug;38(4):62-6.

PMID:1337520
Abstract

The effects of specific agonists and antagonists of adrenoceptors and inhibitors of cAMP phosphodiesterase on electrostimulated phasic contractions in the ureter of guinea pig were studied. It has been shown that there mainly excitatory alpha 1-adrenoceptors in this object, the density of beta-adrenoceptors is slight and functional alpha 2-adrenoceptors are probably absent. Some aspects of adrenergic regulation of the contractile function of guinea pig ureter are discussed.

摘要

研究了肾上腺素能受体的特异性激动剂和拮抗剂以及环磷酸腺苷磷酸二酯酶抑制剂对豚鼠输尿管电刺激引起的相性收缩的影响。结果表明,该标本中主要存在兴奋性α1-肾上腺素能受体,β-肾上腺素能受体密度较低,可能不存在功能性α2-肾上腺素能受体。并讨论了豚鼠输尿管收缩功能的肾上腺素能调节的某些方面。

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