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脑氧合状态:离体灌注大鼠脑的制备及近红外分光光度法

Brain oxygenation state: preparation of isolated perfused rat brain and near-infrared spectrophotometry.

作者信息

Inagaki M, Tamura M

机构信息

Biophysics Division, Hokkaido University, Sapporo, Japan.

出版信息

Adv Exp Med Biol. 1992;316:119-23. doi: 10.1007/978-1-4615-3404-4_13.

DOI:10.1007/978-1-4615-3404-4_13
PMID:1337647
Abstract

The method of blood-free isolated perfused rat brain was described, of which EEG was within the normal range. The simultaneous measurement of heme a+a3 and copper in cytochrome oxidase could be performed under the various conditions such as graded hypoxia and seizure. The relationship between these two chromophores in the brain was same to that of isolated mitochondria.

摘要

描述了无血分离灌注大鼠脑的方法,其脑电图在正常范围内。在分级缺氧和癫痫等各种条件下,可以同时测量细胞色素氧化酶中的血红素a+a3和铜。脑中这两种发色团之间的关系与分离的线粒体相同。

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Brain oxygenation state: preparation of isolated perfused rat brain and near-infrared spectrophotometry.脑氧合状态:离体灌注大鼠脑的制备及近红外分光光度法
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