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唾液腺肿瘤核仁组成区的定量研究

[Quantitative study on nucleolar organizer regions in salivary gland tumours].

作者信息

Wang S Z

机构信息

Affiliated Hospital for Stomatology, Hubei Medical College, Wuhan.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 1992 Mar;27(2):74-6, 127.

PMID:1337733
Abstract

The argyrophil staining technique for nucleolar organizer regions (NOR) had been applied to a series of benign and malignant salivary gland tumours. We have studied 38 salivary gland tumours, 16 benign and 22 malignant. In all specimens clearly defined silver-stained intranuclear AgNOR dots were visible. The differences between the numbers of AgNORs in the benign and malignant groups, notably pleomorphic adenomas, adenoid cystic carcinoma, mucoepidermoid carcinoma and adenocarcinoma, were highly significant. This result suggested that the AgNOR technique is of diagnostic help in distinguishing between these salivary gland tumours.

摘要

核仁组成区嗜银染色技术已应用于一系列涎腺良恶性肿瘤。我们研究了38例涎腺肿瘤,其中16例为良性,22例为恶性。在所有标本中均可见清晰界定的核内嗜银核仁组成区(AgNOR)点状结构。良性组与恶性组,尤其是多形性腺瘤、腺样囊性癌、黏液表皮样癌和腺癌之间的AgNOR数量差异具有高度显著性。这一结果表明,AgNOR技术有助于这些涎腺肿瘤的诊断鉴别。

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