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[牛磺酸与β-丙氨酰-L-组氨酸(肌肽)与次氯酸根阴离子(ClO-)的相互作用]

[The interaction of taurine and beta-alanyl-L-histidine (carnosine) with hypochlorite anion (ClO-)].

作者信息

Gorshkova T N, Formaziuk V E, Sergienko V I, Dudina E I

出版信息

Biull Eksp Biol Med. 1992 Nov;114(11):475-7.

PMID:1337841
Abstract

Dipeptide carnosine and amino acid taurine have been found to actively interact with hypochlorite anion. Chloramine complexes obtained during this reaction were more stable in case of taurine. It is suggested that therapeutic effect of new Russian eye drops taufon and sevitin is due to neutralization of the reaction product hypochlorite anion catalyzed by myeloperoxidase.

摘要

已发现二肽肌肽和氨基酸牛磺酸可与次氯酸根阴离子发生积极相互作用。在该反应中生成的氯胺络合物在牛磺酸的情况下更稳定。有人认为,俄罗斯新型眼药水陶芬和塞维汀的治疗效果是由于髓过氧化物酶催化的次氯酸根阴离子反应产物的中和作用。

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