Chang T K, Wong T T, Ho D M
Department of Pediatrics, Veterans General Hospital-Taipei, National Yang-Ming Medical College, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1992 Dec;50(6):520-4.
Congenital brain tumor is a rare disease in the neonatal period. According to the literatures, they comprise only about 1% of childhood brain tumors. Among the congenital brain tumors, 10%-25% are astrocytomas. Anaplastic astrocytoma is one of the malignant glioma. The prognosis is usually not good in the childhood or adult stage. We report one case of congenital anaplastic astrocytoma who received combination chemotherapy, including vinblastine, cisplatin and etoposide following subtotal resection of tumor. After chemotherapy, he got a favorable outcome. And now, he is still no evidence of tumor recurrence for two years.
先天性脑肿瘤在新生儿期是一种罕见疾病。根据文献记载，它们仅占儿童脑肿瘤的约1%。在先天性脑肿瘤中，10%-25%为星形细胞瘤。间变性星形细胞瘤是恶性胶质瘤之一。在儿童期或成人期，其预后通常不佳。我们报告一例先天性间变性星形细胞瘤患者，该患者在肿瘤次全切除后接受了包括长春碱、顺铂和依托泊苷在内的联合化疗。化疗后，他取得了良好的效果。目前，他已经两年没有肿瘤复发的迹象。
