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[血清特异性抗体在牙周炎鉴别诊断中的应用价值]

[The value of using serum specific antibody in differential diagnosis of periodontitis].

作者信息

OuYang X Y

机构信息

School of Stomatology, Beijing Medical University.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 1992 May;27(3):137-9, 189.

PMID:1338038
Abstract

In the present study, serum anti-Bacteroides gingivalis (Bg) and anti-Actinobacillus actinomycetemcomitans (Aa) antibody titers in RPP, AP patients and healthy subjects were determined by ELISA. Discriminant analysis for differential diagnosis of RPP, AP and healthy subjects was performed using clinical measurements (PD, AL, PII, BI) and serum antibody levels as combined parameters. The results showed significantly different serum antibody levels among the three examined groups. The results also suggested that the combined use of clinical parameters and serum specific antibody titers may be a valuable measure in differential diagnosis of periodontal diseases.

摘要

在本研究中,通过酶联免疫吸附测定法(ELISA)测定了重度慢性牙周炎(RPP)患者、侵袭性牙周炎(AP)患者和健康受试者血清中抗牙龈拟杆菌(Bg)和抗伴放线放线杆菌(Aa)的抗体滴度。以临床测量指标(牙周袋深度、附着丧失、菌斑指数、探诊出血)和血清抗体水平作为联合参数,对RPP患者、AP患者和健康受试者进行鉴别诊断的判别分析。结果显示,在所检测的三组中血清抗体水平存在显著差异。结果还表明,临床参数和血清特异性抗体滴度的联合应用可能是牙周疾病鉴别诊断中的一项有价值的指标。

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