有机阳离子与线粒体膜的相互作用。
The interaction of organic cations with the mitochondrial membrane.
作者信息
Massari S, Pozzan T
出版信息
Experientia. 1976;32(7):868-9. doi: 10.1007/BF02003735.
PMID:133812
Abstract
Weak and strong organic bases behave in an opposite manner in respect to several mitochondrial functions. The former induce a catalytic exchange with K+ in valinomycon-treated, respiratory-inhibited mitochondria, and act as uncouplers in respiring mitochondria. The latter induce a stoicheometric exchange with K+ and are actively taken up by respiring mitochondria.
摘要
弱有机碱和强有机碱在几种线粒体功能方面表现出相反的行为。前者在缬氨霉素处理、呼吸抑制的线粒体中诱导与K⁺的催化交换，并在呼吸的线粒体中充当解偶联剂。后者诱导与K⁺的化学计量交换，并被呼吸的线粒体主动摄取。
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