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[自主神经功能障碍在代谢性营养性肥胖患者脂质及脂蛋白代谢紊乱发病机制中的作用]

[The role of autonomic dysfunction in the pathogenesis of lipid and lipoprotein metabolic disorders in patients with metabolic-alimentary obesity].

作者信息

Panina E B, Botvinnik V S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(5-12):22-4.

PMID:1338147
Abstract

Obesity is a "disease of civilization" that leads to the formation of vascular pathology. Vegetodystonia, a heterogeneous syndrome both as regards the type and clinical course, is a pronounced clinical manifestation of obesity. The role of vegetodystonia in the formation of atherogenic potential of obesity has not been studied yet. 77 patients with metabolic alimentary obesity were examined for blood lipidograms as compared to the vegetative status and anthropometric data. Based on a correlation analysis performed, a relationship was discovered between the changes in the parameters indicated. The character of the correlation was determined by the type of vegetodystonia. The leading part in the formation of atherogenic potential is played by sympathoadrenal influences which are most manifest is permanent vegetovascular dystonia of the vagoinsular type. The treatment of obesity should be carried out with regard to the concrete variety of vegetative dysfunction.

摘要

肥胖是一种“文明病”,会导致血管病变的形成。植物神经功能紊乱是一种在类型和临床过程上都具有异质性的综合征,是肥胖的一种明显临床表现。植物神经功能紊乱在肥胖致动脉粥样硬化潜力形成中的作用尚未得到研究。对77例代谢性营养性肥胖患者进行了血脂谱检查,并与植物神经状态和人体测量数据进行了比较。基于所进行的相关性分析,发现了所指出参数变化之间的关系。相关性的特征由植物神经功能紊乱的类型决定。交感肾上腺影响在致动脉粥样硬化潜力的形成中起主导作用,这在迷走神经型永久性植物血管功能紊乱中最为明显。肥胖的治疗应针对植物神经功能障碍的具体类型进行。

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