Piao S F
Second Teaching Hospital of N. Bethune University of Medical Sciences, Chang chun.
Zhonghua Jie He He Hu Xi Za Zhi. 1992 Aug;15(4):214-6, 254.
The levels of free radicals in the whole blood of the patients with cor pulmonale were determined using the method of electron spin resonance (ESR). The concentrations of serum SOD were determined using RIA. The concentrations of the MDA, vitamin E, selenium and the activities of the SeGSHPx, CAT of the patients were also measured using biochemical methods. The results showed that the level of free radical in the whole blood and serum MDA, SOD increase if compared with that of control group. The activities of SeGSH-Px, CAT and the concentration of vitamin E in serum of the patients are in lower level. These indicate that there is impairment in free radical metabolism of the patients.
采用电子自旋共振（ESR）法测定肺心病患者全血中自由基水平。采用放射免疫分析法（RIA）测定血清超氧化物歧化酶（SOD）浓度。还采用生化方法测定患者丙二醛（MDA）、维生素E、硒的浓度以及硒谷胱甘肽过氧化物酶（SeGSHPx）、过氧化氢酶（CAT）的活性。结果显示，与对照组相比，患者全血自由基水平及血清MDA、SOD升高。患者血清中SeGSH-Px、CAT活性及维生素E浓度处于较低水平。这些表明患者自由基代谢存在障碍。
