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[Control of homologous recombination by mismatch base repair system in bacteria: implications concerning the chromosome stability and the evolution of species].

作者信息

Rayssiguier C

机构信息

Laboratoire de Mutagenèse, Institut J. Monod, Paris, France.

出版信息

C R Seances Soc Biol Fil. 1992;186(6):635-40.

PMID:1339593
Abstract

The generalized mismatch repair system controls, in bacteria, the homologous recombination between diverged (homologous) DNA. It thus constitute, together with the sequence divergence, a barrier to recombination between bacteria of different species as we have shown for E. coli and S. typhimurium. It is moreover, by preventing the recombination between diverged repeated sequences, a key component of the chromosome stability.

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