Merlier O, Ribet M, Mensier E, Ronsmans N, Caulier M T
Clinique chirurgicale Ouest, Hôpital Calmette, CHU, Lille.
Chirurgie. 1992;118(4):229-35.
Among 533 patients who were splenectomized between 1967 and 1981 for a chronic haemopathy, 8 were reoperated because of the reappearance of an accessory spleen, which was responsible for the relapse of the disease. Five patients were followed for idiopathic thrombopenic purpura (ITP), 2 for hereditary spherocytosis and 1 for a Hodgkin disease (this patient had been operated for an abdominal exploration and splenectomy). In all patients, a hepato-splenic scintigram with Tc 99 m permitted the discovery of the accessory spleens and the exploration was completed by the study of the half lifetime and sequestration of platelets or red blood cells. The disappearance of the haemorrhagic syndrome after removal of the accessory spleen was frank and didn't need any complementary treatment for 3 cases of ITP and 2 cases of spherocytosis and was incomplete and had to be completed by a secondary treatment for 2 cases of ITP and for the Hodgkin disease. The analysis and the interpretation of the results of this study can be helpful to establish the diagnosis and decide the treatment of accessory spleens which are discovered by a relapse of a chronic haemopathy, primarily treated by splenectomy.
在1967年至1981年间因慢性血液病而行脾切除术的533例患者中,有8例因副脾再现而再次手术,副脾是导致疾病复发的原因。5例患者因特发性血小板减少性紫癜(ITP)接受随访,2例因遗传性球形红细胞增多症,1例因霍奇金病(该患者曾接受腹部探查和脾切除术)。在所有患者中,用99m锝进行肝脾闪烁扫描可发现副脾,并通过研究血小板或红细胞的半衰期和滞留情况来完成探查。切除副脾后,3例ITP和2例球形红细胞增多症患者出血综合征明显消失,无需任何辅助治疗;2例ITP患者和霍奇金病患者出血综合征消失不完全,必须通过二次治疗来完成。本研究结果的分析和解释有助于确立慢性血液病复发后发现的、最初经脾切除术治疗的副脾的诊断并决定其治疗方法。