Sayegh R, Khoury K, Nassr W
Service de Gastroentérologie, Centre Hospitalier Universitaire Hôtel-Dieu de France, Université Saint-Joseph, Beyrouth, Liban.
J Med Liban. 1992;40(1):11-5.
In order to evaluate the efficacity and tolerance of Famotidine in the treatment of gastric ulcer, in Lebanese patients, we conducted a prospective open study in twenty one patients with benign gastric ulcer. A clinical, endoscopic and biological evaluation was done before, at 4 weeks and if necessary at 8 weeks after the start of 40 mg of Famotidine per day. All patients were carefully monitored at regular intervals for adverse drug reactions by clinical and biological examinations. The healing rate at 4 and 8 weeks was 75% and 91% respectively. The treatment was well tolerated and no modifications in laboratory tests were observed. Famotidine therefore proved effective in the treatment of gastric ulcer and was well tolerated on a short term basis.
为评估法莫替丁治疗黎巴嫩患者胃溃疡的疗效和耐受性，我们对21例良性胃溃疡患者进行了一项前瞻性开放研究。在开始每天服用40毫克法莫替丁之前、4周时以及必要时8周后，进行了临床、内镜和生物学评估。通过临床和生物学检查定期对所有患者仔细监测药物不良反应。4周和8周时的愈合率分别为75%和91%。该治疗耐受性良好，未观察到实验室检查有变化。因此，法莫替丁在治疗胃溃疡方面被证明是有效的，且短期内耐受性良好。
