在体外共栖培养条件下维持的溶组织内阿米巴临床分离株中的胶原酶活性。
Collagenase activity in clinical isolates of Entamoeba histolytica maintained in xenic cultures.
作者信息
Magos M A, de la Torre M, Muñoz M L
机构信息
Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del IPN, México, DF, México.
出版信息
Arch Med Res. 1992;23(2):115-8.
Several isolates of pathogenic and non-pathogenic E. histolytica from xenic cultures were tested for their capacity to digest native type I collagen gels. The results demonstrate that the pathogenic isolate HM48:IMSS has a high collagenolytic activity. The non-pathogenic isolates, HM43:IMSS, HM44:IMSS and HM46:IMSS showed significantly lower collagenolytic activity. Six groups showing different degrees of collagenase activity or non-activity were separated from the non-pathogenic isolates by a Percoll gradient. The groups obtained from the pathogenic isolate HM48:IMSS always displayed enzymatic activity.
对来自复合培养物的几种致病性和非致病性溶组织内阿米巴分离株消化天然I型胶原凝胶的能力进行了测试。结果表明，致病性分离株HM48:IMSS具有较高的胶原酶活性。非致病性分离株HM43:IMSS、HM44:IMSS和HM46:IMSS的胶原酶活性显著较低。通过Percoll梯度从非致病性分离株中分离出六组显示不同程度胶原酶活性或无活性的菌株。从致病性分离株HM48:IMSS获得的组始终表现出酶活性。
Zotero 插件