Avila W S, Grinberg M, Cardoso L F, Faccioli R, Bellotti G, Pileggi F
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP.
Rev Assoc Med Bras (1992). 1992 Oct-Dec;38(4):195-200.
To study pregnancy, delivery, puerperium and the newborn in cases of mitral valve stenosis, asymptomatic at conception.
Sixty-two pregnant women, 30 with mitral valve stenosis (GE group) and 32 without cardiac disease (GN group) had their functional class, kind of delivery, anesthetic technique and newborn characteristics evaluated during gestation.
In GE group 16 (53.3%) patients changed from functional class (FC) I/II to FC III and 10 (33.3%) to FC IV. In GN group 18 (56.2%) changed from FC I to II during the gestation. Delivery was vaginal in 21 patients (70%); anesthetic technique was regional block in 17 (56.6%). These findings were not statistically different between (p > 0.1) the groups. Premature (20.0%) and small babies for gestational age (36.7%) were higher (p > 0.001) in GE group. There were no cases of maternal death.
The majority of GE women who started pregnancy in FC I/II changed to FC III/IV during gestation. Probably adequate medical treatment and valvoplasty in one case allowed fetal viability; but we had higher incidence of pre-term and small for gestation age babies in the GE group.
研究妊娠合并孕前无症状二尖瓣狭窄患者的妊娠、分娩、产褥期及新生儿情况。
62例孕妇,30例合并二尖瓣狭窄(GE组),32例无心脏病(GN组),在孕期对其心功能分级、分娩方式、麻醉技术及新生儿特征进行评估。
GE组中16例(53.3%)患者心功能分级从I/II级转变为III级,10例(33.3%)转变为IV级。GN组中18例(56.2%)在孕期心功能分级从I级转变为II级。21例患者(70%)经阴道分娩;17例(56.6%)采用区域阻滞麻醉技术。两组间这些结果无统计学差异(p>0.1)。GE组早产(20.0%)和小于胎龄儿(36.7%)发生率更高(p>0.001)。无孕产妇死亡病例。
大多数心功能分级为I/II级开始妊娠的GE组女性在孕期转变为III/IV级。可能适当的药物治疗及1例瓣膜成形术使胎儿存活;但GE组早产和小于胎龄儿的发生率更高。