Iung B, Cormier B, Elias J, Michel P L, Sananes S, Uzan S, Vahanian A, Acar J
Service de cardiologie, hôpital Tenon, Paris.
Arch Mal Coeur Vaiss. 1993 Jul;86(7):995-9.
This report analyses the efficacy and tolerance of percutaneous mitral commissurotomy (PMC) in 10 pregnant women with severe mitral stenosis. Pregnancy was the cause of decompensation of the mitral stenosis and surgery was not considered because of the foetal risk. PMC was undertaken after an average of 26 +/- 4 weeks of gestation (range 23-33 weeks). The average age of the patients was 28 +/- 6 years (range 20-41 years). Six patients were in NYHA Class III and 4 in Class IV despite medical treatment. Five patients had mild mitral regurgitation. Foetal protection was ensured by covering the mother's abdomen with a lead apron. The double balloon technique was used in 4 cases and Inoue's balloon in 6 patients. The average duration of fluoroscopy was 17 +/- 10 minutes (range 6-37 minutes). After PMC, the mean pulmonary artery pressure decreased from 47 +/- 12 mmHg to 31 +/- 11 mmHg (p = 0.005); two dimensional echocardiography showed an increase in mitral valve surface area from 1 +/- 0.2 cm2 to 2 +/- 0.3 cm2 (p = 0.005). There were no complications related to the procedure. The foetal heart rate was monitored continuously and no significant modification suggestive of foetal distress was recorded. The abdominal cutaneous dose of irradiation was less than 0.2 millisievert, which was minimal. All patients experienced a functional improvement after PMC. Nine delivered after an average gestation of 38 +/- 2 weeks (range 36-42 weeks) without cardiac decompensation. The average birth weight of the babies was 3.1 +/- 0.3 kg (range 2.9-3.7 kg).(ABSTRACT TRUNCATED AT 250 WORDS)
本报告分析了10例重度二尖瓣狭窄孕妇行经皮二尖瓣交界切开术(PMC)的疗效和耐受性。妊娠是二尖瓣狭窄失代偿的原因,由于胎儿风险未考虑手术治疗。平均妊娠26±4周(范围23 - 33周)后进行PMC。患者平均年龄28±6岁(范围20 - 41岁)。尽管接受了药物治疗,6例患者为纽约心脏病协会(NYHA)Ⅲ级,4例为Ⅳ级。5例患者有轻度二尖瓣反流。通过用铅围裙覆盖母亲腹部确保胎儿得到保护。4例采用双球囊技术,6例采用Inoue球囊。透视平均持续时间为17±10分钟(范围6 - 37分钟)。PMC术后,平均肺动脉压从47±12 mmHg降至31±11 mmHg(p = 0.005);二维超声心动图显示二尖瓣瓣口面积从1±0.2 cm²增加到2±0.3 cm²(p = 0.005)。未发生与手术相关的并发症。持续监测胎儿心率,未记录到提示胎儿窘迫的显著变化。腹部皮肤辐射剂量小于0.2毫希沃特,极小。所有患者PMC术后功能均有改善。9例患者平均妊娠38±2周(范围36 - 42周)后分娩,无心脏失代偿情况。婴儿平均出生体重为3.1±0.3 kg(范围2.9 - 3.7 kg)。(摘要截选至250字)