尼日利亚学童中乙胺嘧啶对疟疾的抑制作用。
Suppression of malaria with pyrimethamine in Nigerian schoolchildren.
作者信息
ARCHIBALD H M, BRUCE-CHWATT L J
出版信息
Bull World Health Organ. 1956;15(3-5):775-84.
Abstract
The authors describe a two-year investigation carried out on a group of Nigerian schoolchildren with the object of assessing the effect of suppressing malaria infection with pyrimethamine on the physical development of the African child. The results showed that the average gain in weight of the treated children over the period of the investigation was significantly greater than that of the untreated children. Despite the relatively high weekly dose of the drug no side-effects were observed, and no alarming manifestation of malaria was noted when administration of the drug was discontinued.
摘要
作者描述了一项针对一群尼日利亚学童进行的为期两年的调查，目的是评估用乙胺嘧啶抑制疟疾感染对非洲儿童身体发育的影响。结果显示，在调查期间，接受治疗的儿童的平均体重增加明显高于未接受治疗的儿童。尽管该药物的每周剂量相对较高，但未观察到副作用，并且在停药后也未发现疟疾的惊人表现。
相似文献
1
Suppression of malaria with pyrimethamine in Nigerian schoolchildren.尼日利亚学童中乙胺嘧啶对疟疾的抑制作用。
Bull World Health Organ. 1956;15(3-5):775-84.
2
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.青蒿琥酯-阿莫地喹与氯喹-乙胺嘧啶-磺胺多辛治疗尼日利亚儿童单纯性恶性疟原虫疟疾的开放随机研究
Trop Med Int Health. 2005 Nov;10(11):1161-70. doi: 10.1111/j.1365-3156.2005.01503.x.
3
4
Evaluation of four therapeutic regimens for falciparum malaria in Mozambique, 1986.1986年莫桑比克四种恶性疟治疗方案的评估
Bull World Health Organ. 1988;66(2):219-26.
5
Antimalarials during pregnancy: a cost-effectiveness analysis.孕期抗疟药：成本效益分析
Bull World Health Organ. 1995;73(2):207-14.
6
Observations on the early course of untreated falciparum malaria in semi-immune African children following a short period of protection.对短期获得保护后未治疗的非洲半免疫儿童恶性疟原虫疟疾早期病程的观察
Bull World Health Organ. 1966;34(2):269-72.
7
8
Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children.蒿甲醚-本芴醇与阿莫地喹-磺胺多辛-乙胺嘧啶对儿童恶性疟原虫有性期寄生虫的活性
Chemotherapy. 2008;54(3):201-8. doi: 10.1159/000140463. Epub 2008 Jun 18.
9
10
Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria.蒿甲醚-本芴醇和阿莫地喹-磺胺多辛-乙胺嘧啶对尼日利亚西南部非复杂性恶性疟原虫疟疾患儿配子体携带情况的治疗效果及影响
Am J Trop Med Hyg. 2007 Aug;77(2):235-41.
引用本文的文献
1
Chemoprevention for the Populations of Malaria Endemic Africa.针对非洲疟疾流行地区人群的化学预防
Diseases. 2022 Nov 8;10(4):101. doi: 10.3390/diseases10040101.
2
Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review.大规模抗疟药物管理中的社区参与和人群覆盖：一项系统文献综述
Malar J. 2016 Nov 2;15(1):523. doi: 10.1186/s12936-016-1593-y.
3
Mass drug administration for malaria.疟疾群体服药
Cochrane Database Syst Rev. 2013 Dec 9;2013(12):CD008846. doi: 10.1002/14651858.CD008846.pub2.
4
Intermittent preventive treatment for malaria in children living in areas with seasonal transmission.对生活在季节性传播地区的儿童进行疟疾间歇性预防治疗。
Cochrane Database Syst Rev. 2012 Feb 15;2012(2):CD003756. doi: 10.1002/14651858.CD003756.pub4.
5
MALARIA control.疟疾控制
Br Med J. 1957 May 11;1(5027):1108-9.
6
The impact of malaria chemoprophylaxis on the immune status of Africans.疟疾化学预防对非洲人免疫状态的影响。
Bull World Health Organ. 1984;62 Suppl(Suppl):69-75.
7
Low birth-weight and malarial infection of the placenta.低出生体重与胎盘疟疾感染
Bull World Health Organ. 1968;38(1):69-78.
8
Chronic leukaemia: an African experience.
Med Oncol Tumor Pharmacother. 1989;6(3):189-94. doi: 10.1007/BF02985189.
本文引用的文献
1
Preliminary field trials on a new schizonticide.一种新型裂殖体杀灭剂的初步田间试验。
Br Med J. 1951 Oct 6;2(4735):821-3. doi: 10.1136/bmj.2.4735.821.
2
Changes in the mean stature and weight of British children over the past seventy years.过去七十年来英国儿童平均身高和体重的变化。
Br Med J. 1953 Oct 24;2(4842):897-902. doi: 10.1136/bmj.2.4842.897.
3
Field trials of new antimalarials in West Africa.新型抗疟药物在西非的现场试验。
Br Med J. 1953 Mar 7;1(4809):539-41. doi: 10.1136/bmj.1.4809.539.
4
Malaria in African infants and children in Southern Nigeria.尼日利亚南部非洲婴幼儿中的疟疾
Ann Trop Med Parasitol. 1952 Sep;46(2):173-200. doi: 10.1080/00034983.1952.11685522.
Zotero 插件