Cherniĭ O F, Seredenko M M, Sidelńykov V M
Fiziol Zh (1978). 1992 Nov-Dec;38(6):25-30.
Lipine, a new antihypoxic drug, has been studied for its effect on respiration and pulmonary gaseous exchange in 47 newborn children, health and with respiratory distress syndrome stresses (SRD) after perinatal asphyxia. It is shown that lipine inhalations cause a considerable increase in duration of respiratory cycle, decrease of respiration frequency, ratio of ispiration di time, to expiration time, increase of alveolar ventilation volume and decrease of respiratory dead space ventilation volume in all lung ventilation volume in newborns with SRD, to a larger degree pronounced in premature children. A conclusion is made on the positive effect of lipine on the state of respiration function and gaseous exchange in lungs in newborn children with symptoms of SRD.
脂平，一种新型抗缺氧药物，已针对其对47例新生儿呼吸及肺气体交换的影响进行了研究，这些新生儿健康或患有围产期窒息后呼吸窘迫综合征（SRD）。结果表明，对患有SRD的新生儿进行脂平吸入治疗后，呼吸周期时长显著增加，呼吸频率降低，吸气时间与呼气时间之比增大，肺泡通气量增加，呼吸无效腔通气量占肺总通气量的比例降低，这一效果在早产儿中更为明显。得出结论：脂平对患有SRD症状的新生儿肺呼吸功能及气体交换状态具有积极作用。
