Goedde T A, Rodriguez-Bigas M A, Herrera L, Petrelli N J
Roswell Park Cancer Institute, Department of Surgical Oncology, Buffalo, New York 14263.
Surg Oncol. 1992 Oct;1(5):357-61. doi: 10.1016/0960-7404(92)90036-k.
A retrospective review of the medical records of 30 patients with familial adenomatous polyposis who underwent oesophagogastroduodenoscopy was performed to evaluate the spectrum of gastroduodenal polyps. Twenty-five patients (83%) had gastroduodenal polyps. Eighteen patients (60%) had gastric polyps and 21 patients (70%) had duodenal polyps. Five patients (17%) had gastric and 20 patients (67%) had duodenal adenomatous polyps. Three patients (10%) died from an upper gastrointestinal tract adenocarcinoma. Three of nine patients with periampullary adenomas had a normal-appearing papilla of Vater. Since gastroduodenal polyps are common in familial adenomatous polyposis, oesophagogastroduodenoscopy should be performed at the time of diagnosis. Biopsy of polyps as well as biopsy of a normal-appearing papilla of Vater should be performed. Due to their malignant potential, if identified, gastroduodenal adenomatous polyps should be destroyed.
对30例接受食管胃十二指肠镜检查的家族性腺瘤性息肉病患者的病历进行回顾性分析，以评估胃十二指肠息肉的情况。25例患者（83%）有胃十二指肠息肉。18例患者（60%）有胃息肉，21例患者（70%）有十二指肠息肉。5例患者（17%）有胃腺瘤性息肉，20例患者（67%）有十二指肠腺瘤性息肉。3例患者（10%）死于上消化道腺癌。9例壶腹周围腺瘤患者中有3例十二指肠乳头外观正常。由于胃十二指肠息肉在家族性腺瘤性息肉病中很常见，因此应在诊断时进行食管胃十二指肠镜检查。应对息肉以及外观正常的十二指肠乳头进行活检。由于胃十二指肠腺瘤性息肉有恶变潜能，一旦发现应予以切除。
