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A method of conducting a biological assay on a preparation giving repeated graded responses illustrated by the estimation of histamine.一种对能产生如组胺估计值所示的重复分级反应的制剂进行生物学测定的方法。
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2
Pharmacological studies on the antispasmodic, beta-diethylaminoethyl 1-cyclohexylcyclo-hexanecarboxylate hydrochloride.盐酸β - 二乙氨基乙基1 - 环己基环己烷羧酸酯的解痉药理研究
J Am Pharm Assoc Am Pharm Assoc. 1950 Jun;39(6):305-11. doi: 10.1002/jps.3030390602.
3
The parasympathetic depressant and antihistaminic action of substituted 1,3-dioxolanes.取代的1,3 - 二氧戊环的副交感神经抑制和抗组胺作用。
J Pharmacol Exp Ther. 1949 Oct;97(2):157-70.
4
Homatropine methylbromide; a pharmacological reevaluation.甲溴后马托品；药理学再评价
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5
An investigation of the pharmacological actions of three potent antispasmodic compounds and their corresponding metho-salts.三种强效抗痉挛化合物及其相应的甲盐的药理作用研究。
J Pharmacol Exp Ther. 1954 Mar;110(3):282-92.
6
The pharmacological activity of DL-alpha, alpha-diphenyl, gamma-dimethylaminovaleramide (centrine).DL-α,α-二苯基,γ-二甲基氨基戊酰胺（森特林）的药理活性。
J Pharmacol Exp Ther. 1954 Jan;110(1):55-67.

抗乙酰胆碱药物对家兔毛果芸香碱诱导流涎的拮抗作用测定。

The assay of anti-acetylcholine agents for antagonism of pilocarpine-induced salivation in rabbits.

作者信息

BROWN D M, QUINTON R M

出版信息

Br J Pharmacol Chemother. 1957 Mar;12(1):53-60. doi: 10.1111/j.1476-5381.1957.tb01362.x.

DOI:10.1111/j.1476-5381.1957.tb01362.x
PMID:13413152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1509633/
Abstract

Experimental conditions affecting tests of atropine-like agents for antagonism of pilocarpine-induced salivation in rabbits have been examined. A simple method of assay of such agents is described. It gave results of fair accuracy and reproducibility, permitted a full statistical analysis, and provided an estimate of the error.

摘要

研究了影响用阿托品样药物拮抗毛果芸香碱诱导家兔唾液分泌试验的实验条件。描述了一种此类药物的简易测定方法。该方法给出了相当准确且可重复的结果，允许进行全面的统计分析，并提供了误差估计。