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[从癌症患者中分离出的念珠菌属酵母对多烯类抗真菌药物的敏感性]

[The sensitivity of yeasts from the Candida genus isolated from cancer patients to polyene antifungals].

作者信息

Alves S H, Cury A E

机构信息

Laboratório de Análises Clínicas, Hospital Universitário, Universidade Federal de Santa Maria, RS, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 1992 May-Jun;34(3):251-4.

PMID:1342079
Abstract

Candida strains susceptibility from cancer patients were compared with Candida strains susceptibility from patients, without cancer by MIC (minimal inhibitory concentration) and MFC (minimal fungicidal concentration) to Amphotericin B and Nystatin. Broth dilution method and agar dilution method were the procedure employed. The authors find no significant differences between the studied groups. The problem of Candida resistance to polyene antifungals is discussed.

摘要

通过最小抑菌浓度(MIC)和最小杀菌浓度(MFC),比较了癌症患者念珠菌菌株与非癌症患者念珠菌菌株对两性霉素B和制霉菌素的敏感性。采用肉汤稀释法和琼脂稀释法。作者发现研究组之间无显著差异。文中讨论了念珠菌对多烯类抗真菌药物的耐药问题。

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