Marinov B, Tsachev R, Ruseva R, Penev I, Nikolov V
Akush Ginekol (Sofiia). 1992;31(2):5-7.
The neurotoxic effect of lead is well known, but the investigations of the pregnant women are still few. The aim of the present study is to establish whether there is difference in the concentration of lead in the blood of the pregnant women with missed abortion in comparison with women with normally developing pregnancy in the same gestational age. There were examined 35 patients with missed abortion and a control group of 26 women with normal pregnancy in the same gestational age. There were established statistically significant higher levels of lead (p < 0.001) in women with normal pregnancy (124.46 +/- 46.65 micrograms/l) in comparison with cases with missed abortion (183.73 +/- 24.16 micrograms/l). There were discussed the possible mechanisms, which can be responsible for the observed changes.
铅的神经毒性作用众所周知，但针对孕妇的相关研究仍然较少。本研究的目的是确定与相同孕周正常妊娠的女性相比，稽留流产孕妇血液中的铅浓度是否存在差异。研究检查了35例稽留流产患者以及26例相同孕周正常妊娠女性组成的对照组。结果发现，正常妊娠女性（124.46±46.65微克/升）的铅水平在统计学上显著高于稽留流产患者（183.73±24.16微克/升）（p<0.001）。文中还讨论了可能导致观察到的这些变化的机制。
