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[乳腺癌患者的红细胞功能状态和磷脂组成]

[The erythrocyte functional status and phospholipid composition in breast cancer patients].

作者信息

Domanskiĭ V Iu

出版信息

Vopr Onkol. 1992;38(10):1194-202.

PMID:1343145
Abstract

A study of the osmotic resistance of both red blood cells and phospholipids of whole blood and isolated red blood cells showed breast cancer with symptoms of metastasis to involve perverted influence of calcium ions on osmoerythrograms. It is also characterized by similarly high levels of lysophospholipids both in whole blood and in isolated red blood cells and phosphatidylinositol levels which are lower than in metastasis-free cases. Red blood cells from cases of metastatic spreading revealed relatively lower values of the phosphatidylcholine/phosphatidylethanolamine ratio, too.

摘要

一项对全血和分离的红细胞中的红细胞及磷脂的渗透压耐受性研究表明,伴有转移症状的乳腺癌涉及钙离子对红细胞渗透图的异常影响。其特征还在于全血和分离的红细胞中溶血磷脂水平同样较高,而磷脂酰肌醇水平低于无转移病例。发生转移扩散病例的红细胞中磷脂酰胆碱/磷脂酰乙醇胺比值也相对较低。

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