Dollfus S, Petit M, Ménard J F, Lesieur P
Praticien Hospitalier, CHS du Rouvray, Sotteville Les Rouen, France.
Ann Med Psychol (Paris). 1992 Apr-May;150(4-5):327-31.
The discrepancies of studies on symptomatology and treatment of schizophrenia could be related to the selection of different patients diagnosed by one diagnostic system, different from a study to another. Therefore, we tested whether 14 diagnostic systems could include 51 patients differently as regard to the intensity of positive, negative or depressive symptomatology and to the phase of illness. The distribution of the patients in different sets of diagnosis has been carried out by a computer program and the symptomatology has been evaluated with PANSS and MADRS. Some diagnostic criteria like DSMIII-R, Langfeldt, Taylor, ICD 9 include negative and depressive patients preferentially. Others systems like Berner, Catego, ICD 9, New-Haven, Schneider, include more patients with acute than residual symptoms. These results show the importance of the choice of one or more diagnostic criteria depending on the aim of the study.
关于精神分裂症症状学和治疗的研究差异可能与使用同一诊断系统对不同患者的选择有关，不同研究之间存在差异。因此，我们测试了14种诊断系统是否会因阳性、阴性或抑郁症状的强度以及疾病阶段的不同而对51名患者有不同的纳入情况。通过计算机程序对患者进行不同诊断组的分配，并使用阳性和阴性症状量表（PANSS）及蒙哥马利-艾森伯格抑郁量表（MADRS）对症状学进行评估。一些诊断标准，如《精神疾病诊断与统计手册》第三版修订本（DSMIII-R）、朗费尔特标准、泰勒标准、《国际疾病分类》第九版（ICD 9），优先纳入阴性和抑郁患者。其他系统，如伯尔纳标准、卡特戈标准、《国际疾病分类》第九版、纽黑文标准、施奈德标准，则纳入更多急性症状而非残留症状的患者。这些结果表明，根据研究目的选择一种或多种诊断标准非常重要。
