RUSKA H, MOORE D H, WEINSTOCK J
J Biophys Biochem Cytol. 1957 Mar 25;3(2):249-54. doi: 10.1083/jcb.3.2.249.
The three dimensional arrangement of the compartments on the base of proximal convoluted tubule cells of rat kidney is described. An extracellular basal labyrinth is found to be enclosed by these compartments. The compartments with their mitochondria and the basal labyrinth are regarded as forming a functional unit. It is supposed that this basal unit serves for excretion of reabsorbed fluid from the cell into the labyrinth and for the development of hydrostatic pressure in the labyrinth to overcome the capillary pressure and to pass the reabsorbed fluid into the blood stream.
描述了大鼠肾脏近端曲管细胞基部各间隔的三维排列。发现这些间隔包围着一个细胞外基底迷路。带有线粒体的间隔和基底迷路被视为形成一个功能单元。据推测,这个基部单元用于将细胞内重吸收的液体排泄到迷路中,并在迷路中形成流体静压以克服毛细血管压力,从而将重吸收的液体输送到血流中。