Kumar H S, Bihani V, Kumar V, Chaudhary R K, Kumar L, Punia D P
Department of Radiotherapy, Department of Dental Surgery, S.P. Medical College, Bikaner, India.
Indian J Dent Res. 1992 Apr-Jun;3(2):47-50.
A retrospective analysis of 1140 cases of cancer of oral cavity and oropharynx treated with definitive radiotherapy was carried out with regard to the incidence and precipitating factors of mandibular osteoradionecrosis. 14 cases developed osteoradionecrosis out of which 10 had spontaneous mandibular necrosis and 4 had dental extractions in the area where osteoradionecrosis developed. Amongst the 10 cases of spontaneous osteoradionecrosis, 8 patients received doses of 6500 cGy in 6 1/2 weeks or 7000 cGy in 7 weeks by megavoltage cobalt 60 teletherapy and the remaining two patients received the doses of 6000 cGy in 6 weeks. The aforesaid 4 patients of osteoradionecrosis in the area of dental extractions had received doses of only 6000 cGy in 6 weeks.
对1140例接受根治性放疗的口腔癌和口咽癌患者进行了回顾性分析，以研究下颌骨放射性骨坏死的发生率和诱发因素。14例发生了放射性骨坏死，其中10例为自发性下颌骨坏死，4例在放射性骨坏死发生区域进行了拔牙。在10例自发性放射性骨坏死病例中，8例患者通过兆伏级钴60远距离治疗在6.5周内接受了6500 cGy的剂量或在7周内接受了7000 cGy的剂量，其余2例患者在6周内接受了6000 cGy的剂量。上述4例拔牙区域放射性骨坏死患者在6周内仅接受了6000 cGy的剂量。
