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[The synthesis of new pyrrolidone derivatives with psychotropic action].

作者信息

Stefănescu E, Petrovanu M, Ciocoiu I, Caproşu M, Bîcu E

机构信息

Universitatea de Medicină şi Farmacie Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1992 Jul-Dec;96(3-4):241-2.

PMID:1344862
Abstract

The synthesis of ten new heterocyclic compounds obtained by the addition of pyrrolidone to heterocumulenes and its condensation or of its sodic derivative with acid chlorides is presented. The synthetized pyrolidonic derivatives were subjected to a preliminary study for determining their possible psychotropic action. The pharmacological screening evidenced a significant hypothermisante and neurodynamic-nootropic action of some synthetized compounds.

摘要

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