Janev E, Taskov H, Kostowa L
Z Alternsforsch. 1976;31(1):65-71.
The authors study the morphology of the cells in the peritoneal exsudate and the phosphatase activity of the peritoneal macrophages, obtained from rats with Selye's Progeria-like syndrome. Judging by their morphologic characteristics the macrophages of the experimentally aged rats, before and after contact with Brucella abortus 19 do not differ from those obtained from the unsubjected to experimental ageing rats. The acid phosphatase activity and the adenosinetriphosphatase activity of the macrophages prior to contact with Brucella abortus 19 are nearly identical for both groups of animals. Following contact the activity of the enzymes increases but this increase is slower by aged rats and reaches its maximum 1--2 days later.
作者研究了从患有塞利氏早老样综合征的大鼠获得的腹膜渗出液中的细胞形态以及腹膜巨噬细胞的磷酸酶活性。从实验性衰老大鼠接触布鲁氏菌19前后的巨噬细胞形态特征判断,它们与未进行实验性衰老的大鼠的巨噬细胞并无差异。两组动物在接触布鲁氏菌19之前,巨噬细胞的酸性磷酸酶活性和三磷酸腺苷酶活性几乎相同。接触后,酶的活性增加,但衰老大鼠的增加速度较慢,且在1 - 2天后达到最大值。