Herzog H, Oliveto E P
L&H Herzog Associates, Inc., Glen Ridge, New Jersey 07028.
Steroids. 1992 Dec;57(12):617-23. doi: 10.1016/0039-128x(92)90014-z.
A firsthand historical account of some of the significant contributions of the steroid research group at the Schering Corporation (Bloomfield, NJ, USA) to the discovery and/or development of important therapeutic agents is presented. These include the discovery of the antiinflammatory corticosteroid drugs prednisone, prednisolone, and betamethasone, all of which, more than 30 years after their introduction, continue to enjoy wide use in human and animal medical practice throughout the world.
本文介绍了先灵葆雅公司(美国新泽西州布卢姆菲尔德)类固醇研究团队对重要治疗药物的发现和/或开发所做的一些重大贡献的第一手历史记录。这些贡献包括发现抗炎皮质类固醇药物泼尼松、泼尼松龙和倍他米松,在它们问世30多年后,至今仍在全球人类和动物医疗实践中广泛使用。