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1
The distribution of radioactivity in tissues of the rat following the administration of a nitrogen mustard derivative; p-di-(2-chloroethyl) amino-DL-phenyl[beta-14C] alanine.给予氮芥衍生物；对-二（2-氯乙基）氨基-DL-苯基[β-14C]丙氨酸后大鼠组织中的放射性分布。
Br J Cancer. 1957 Jun;11(2):258-67. doi: 10.1038/bjc.1957.33.
2
[Contribution to the physico-chemical properties of mouse-fixed measles virus. I. Influence of 3-bis(2-chloroethyl)-dl-alanine (No. 243 derivative of nitrogen mustard)].
Nihon Saikingaku Zasshi. 1961 Jun;16:485-9.
3
Preliminary clinical trial of p-di-2-chloroethyl-amino-L-phenylalanine (CB 3025, melphalan) and of di-2-chloroethyl methanesulfonate (CB 1506).
Ann N Y Acad Sci. 1958 Apr 24;68(3):1126-7. doi: 10.1111/j.1749-6632.1958.tb42674.x.
4
The effects of a nitrogen mustard derivative of phenylalanine on experimental tumours.苯丙氨酸氮芥衍生物对实验性肿瘤的作用
Br J Cancer. 1956 Dec;10(4):703-14. doi: 10.1038/bjc.1956.85.
5
[Study of the antimitotic activity of N,N-bis(beta-chloroethyl)-p-aminophenylalanine (L and DL forms) on the meristematic cells of Allium sativum L].
C R Seances Soc Biol Fil. 1959;153:1126-9.
6
[Cytostatic effect of bis-(beta-chloroethyl)p-aminophenylalanine in Oberling myeloma-bearing rats].
Tumori. 1957 Nov-Dec;43(6):739-52. doi: 10.1177/030089165704300605.
7
[Clinical study of the antineoplastic effect of DL-p-bis(beta-chloroethyl) aminophenylalanine].
Minerva Med. 1956 Aug 11;47(63-64):340-2.
8
The absorption of amino acid derivatives of nitrogen mustard from rat intestine in vitro.氮芥氨基酸衍生物在大鼠肠道中的体外吸收
Biochem Pharmacol. 1962 Apr-May;11:371-6. doi: 10.1016/0006-2952(62)90058-8.
9
Studies with mustards. III. In vivo fixation of C14 from nitrogen mustard-C14H3 in nucleic acid fractions of animal tissues.
Arch Biochem Biophys. 1957 Dec;72(2):465-75. doi: 10.1016/0003-9861(57)90222-9.
10
Effect of phenylalanine nitrogen mustard on tissues in culture.
Antibiot Chemother (Northfield). 1957 Sep;7(9):493-6.

引用本文的文献

1
Studies on the incorporation of an unnatural amino acid, p-di-(2-hydroxy[14C2]ethyl)amino-L-phenylalanine, into proteins.关于将一种非天然氨基酸，对 - 二 -（2 - 羟基[14C2]乙基）氨基 - L - 苯丙氨酸掺入蛋白质的研究。
Br J Cancer. 1959 Jun;13(2):313-7. doi: 10.1038/bjc.1959.38.
2
Comparative physico-chemical properties, biological effects, and disposition in mice of four nitrogen mustards.
Cancer Chemother Pharmacol. 1980;5(1):1-9. doi: 10.1007/BF00578555.
3
Melphalan estimation by quantitative thin-layer chromatography. Observations on melphalan hydrolysis in vitro and pharmacokinetics in rabbits.
Cancer Chemother Pharmacol. 1981;5(3):181-4. doi: 10.1007/BF00258477.
4
Tissue distribution and macromolecular interactions of 14[C-ring] melphalan in the rat.
Cancer Chemother Pharmacol. 1982;8(3):271-6. doi: 10.1007/BF00254049.
5
Carcinogenicity of alkylating agents.烷化剂的致癌性。
Public Health Rep (1896). 1966 Sep;81(9):772-6.
6
Relevance of the hydrolysis and protein binding of melphalan to the treatment of multiple myeloma.
Cancer Chemother Pharmacol. 1989;23(2):76-80. doi: 10.1007/BF00273521.

本文引用的文献

1
Characteristics of the amino acid-incorporating system of liver homogenates.肝脏匀浆氨基酸掺入系统的特性
J Biol Chem. 1952 Jan;194(1):359-75.
2
The effects of a nitrogen mustard derivative of phenylalanine on experimental tumours.苯丙氨酸氮芥衍生物对实验性肿瘤的作用
Br J Cancer. 1956 Dec;10(4):703-14. doi: 10.1038/bjc.1956.85.
3
The deproteinisation of nucleoproteins.核蛋白的脱蛋白作用。
Biochim Biophys Acta. 1954 Aug;14(4):559-66. doi: 10.1016/0006-3002(54)90236-x.
4
Incorporation in vitro of labeled amino acids into proteins of rabbit reticulocytes.体外将标记氨基酸掺入兔网织红细胞的蛋白质中。
J Biol Chem. 1952 May;196(2):669-94.

The distribution of radioactivity in tissues of the rat following the administration of a nitrogen mustard derivative; p-di-(2-chloroethyl) amino-DL-phenyl[beta-14C] alanine.

作者信息

COHN P

出版信息

Br J Cancer. 1957 Jun;11(2):258-67. doi: 10.1038/bjc.1957.33.

DOI:10.1038/bjc.1957.33
PMID:13460149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2073732/
Abstract
摘要