• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A study of the desensitization produced by acetylcholine at the motor end-plate.

作者信息

KATZ B, THESLEFF S

出版信息

J Physiol. 1957 Aug 29;138(1):63-80. doi: 10.1113/jphysiol.1957.sp005838.

DOI:10.1113/jphysiol.1957.sp005838
PMID:13463799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1363030/
Abstract
摘要

相似文献

1
A study of the desensitization produced by acetylcholine at the motor end-plate.一项关于乙酰胆碱在运动终板产生脱敏作用的研究。
J Physiol. 1957 Aug 29;138(1):63-80. doi: 10.1113/jphysiol.1957.sp005838.
2
A study of the interaction between neuromuscular blocking agents and acetylcholine at the mammalian motor endplate.一项关于哺乳动物运动终板处神经肌肉阻滞剂与乙酰胆碱相互作用的研究。
Acta Anaesthesiol Scand. 1958;2(2):69-79. doi: 10.1111/j.1399-6576.1958.tb05252.x.
3
Motor end-plate 'desensitization' by repetitive nerve stimuli.重复神经刺激导致运动终板“脱敏”
J Physiol. 1959 Oct;148(3):659-64. doi: 10.1113/jphysiol.1959.sp006314.
4
The identity of intrinsic and extrinsic acetylcholine receptors in the motor end-plate.运动终板中内在和外在乙酰胆碱受体的特性
Proc R Soc Lond B Biol Sci. 1957 May 7;146(924):357-61. doi: 10.1098/rspb.1957.0016.
5
A kinetic analysis of the desensitization at the frog sartorius muscle end-plate.蛙缝匠肌终板脱敏的动力学分析。
Kurume Med J. 1982;29(4):183-7. doi: 10.2739/kurumemedj.29.183.
6
End-plate voltage noise during prolonged application of acetylcholine in cat tenuissimus muscle [proceedings].猫薄肌中长时间应用乙酰胆碱期间的终板电压噪声[会议论文]
J Physiol. 1978 May;278(Suppl):4P-5P.
7
The interaction between edrophonium (tensilon) and acetylcholine at the motor end-plate.依酚氯铵(腾喜龙)与乙酰胆碱在运动终板处的相互作用。
Br J Pharmacol Chemother. 1957 Jun;12(2):260-4. doi: 10.1111/j.1476-5381.1957.tb00131.x.
8
[Effect of vinblastine and colchicine on the postsynaptic membrane of the myoneural junction in the frog].[长春花碱和秋水仙碱对青蛙肌神经接头突触后膜的作用]
Neirofiziologiia. 1988;20(1):75-81.
9
Motor end plate changes in myasthenia gravis.重症肌无力的运动终板改变
Am J Phys Med. 1959 Aug;38:159-62.
10
[Postsynaptic potentiation and desensitization at the myoneural synapse of the frog induced by rhythmic stimulation of a motor nerve].[运动神经节律性刺激诱导青蛙肌神经突触的突触后增强和脱敏]
Neirofiziologiia. 1986;18(5):645-54.

引用本文的文献

1
Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state modeling.通过分子动力学模拟和马尔可夫状态建模揭示的α7烟碱型乙酰胆碱受体脱敏的隐藏复杂性。
Proc Natl Acad Sci U S A. 2025 Feb 18;122(7):e2420993122. doi: 10.1073/pnas.2420993122. Epub 2025 Feb 13.
2
Novel interplay between agonist and calcium binding sites modulates drug potentiation of α7 acetylcholine receptor.激动剂和钙结合位点之间的新相互作用调节 α7 乙酰胆碱受体激动剂的药物增效作用。
Cell Mol Life Sci. 2024 Aug 7;81(1):332. doi: 10.1007/s00018-024-05374-1.
3
Crisis in the gut: navigating gastrointestinal challenges in Gulf War Illness with bioengineering.肠道危机:生物工程应对海湾战争病的胃肠道挑战
Mil Med Res. 2024 Jul 8;11(1):45. doi: 10.1186/s40779-024-00547-2.
4
Pharmacological Treatments for Congenital Myasthenic Syndromes Caused by Mutations.先天性肌营养不良症致药物治疗突变。
Curr Neuropharmacol. 2023;21(7):1594-1605. doi: 10.2174/1570159X21666230126145652.
5
Insights Into the Differential Desensitization of 42 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors.通过对突变受体的正变构调节获得的 42 种烟碱型乙酰胆碱受体亚型的差异化脱敏的深入了解。
Mol Pharmacol. 2023 Feb;103(2):63-76. doi: 10.1124/molpharm.122.000591. Epub 2022 Nov 22.
6
Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model.在一种新型大鼠化学遗传学模型中,脑源性神经营养因子/原肌球蛋白相关激酶B信号传导影响膈肌神经肌肉传递。
Front Cell Neurosci. 2022 Oct 28;16:1025463. doi: 10.3389/fncel.2022.1025463. eCollection 2022.
7
Validate the force-velocity relation of the Hill's muscle model from a molecular perspective.从分子角度验证希尔肌肉模型的力-速度关系。
Front Bioeng Biotechnol. 2022 Oct 14;10:1006571. doi: 10.3389/fbioe.2022.1006571. eCollection 2022.
8
Differential Activation and Desensitization States Promoted by Noncanonical 7 Nicotinic Acetylcholine Receptor Agonists.非经典 7 型烟碱型乙酰胆碱受体激动剂诱导的激活和脱敏状态的差异。
J Pharmacol Exp Ther. 2022 Nov;383(2):157-171. doi: 10.1124/jpet.122.001354. Epub 2022 Sep 2.
9
Structure and Function of the Mammalian Neuromuscular Junction.哺乳动物神经肌肉接头的结构与功能。
Compr Physiol. 2022 Aug 11;12(4):3731-3766. doi: 10.1002/cphy.c210022.
10
Structural mechanism of muscle nicotinic receptor desensitization and block by curare.肌肉烟碱型受体脱敏和阻断的结构机制 由箭毒引起。
Nat Struct Mol Biol. 2022 Apr;29(4):386-394. doi: 10.1038/s41594-022-00737-3. Epub 2022 Mar 17.

本文引用的文献

1
The electromotive action of acetylcholine at the motor end-plate.乙酰胆碱在运动终板处的电动力作用。
J Physiol. 1950 Oct 16;111(3-4):408-22. doi: 10.1113/jphysiol.1950.sp004492.
2
Local activity at a depolarized nerve-muscle junction.去极化神经肌肉接头处的局部活动。
J Physiol. 1955 May 27;128(2):396-411. doi: 10.1113/jphysiol.1955.sp005315.
3
On the localization of acetylcholine receptors.关于乙酰胆碱受体的定位
J Physiol. 1955 Apr 28;128(1):157-81. doi: 10.1113/jphysiol.1955.sp005297.
4
The interaction between edrophonium (tensilon) and acetylcholine at the motor end-plate.依酚氯铵(腾喜龙)与乙酰胆碱在运动终板处的相互作用。
Br J Pharmacol Chemother. 1957 Jun;12(2):260-4. doi: 10.1111/j.1476-5381.1957.tb00131.x.
5
Interaction at end-plate receptors between different choline derivatives.不同胆碱衍生物在终板受体处的相互作用。
Proc R Soc Lond B Biol Sci. 1957 May 7;146(924):369-81. doi: 10.1098/rspb.1957.0018.
6
A study of curare action with an electrical micromethod.一项用电学微方法进行的箭毒作用研究。
Proc R Soc Lond B Biol Sci. 1957 May 7;146(924):339-56. doi: 10.1098/rspb.1957.0015.
7
A modification of receptor theory.受体理论的一种修正。
Br J Pharmacol Chemother. 1956 Dec;11(4):379-93. doi: 10.1111/j.1476-5381.1956.tb00006.x.
8
The ultrastructure of a reptilian myoneural junction.一种爬行动物肌神经接头的超微结构。
J Biophys Biochem Cytol. 1956 Jul 25;2(4):381-94. doi: 10.1083/jcb.2.4.381.
9
A further study of the statistical composition on the end-plate potential.关于终板电位统计构成的进一步研究。
J Physiol. 1955 Oct 28;130(1):114-22. doi: 10.1113/jphysiol.1955.sp005397.
10
Quantal components of the end-plate potential.终板电位的量子成分。
J Physiol. 1954 Jun 28;124(3):560-73. doi: 10.1113/jphysiol.1954.sp005129.