二氧化碳和氧气与血液交换过程中pH值的计算。

Calculations for pH during CO2 and O2 exchange with blood.

作者信息

Heineken F G, Lobdell D D

出版信息

Respir Physiol. 1976 Nov;28(2):277-87. doi: 10.1016/0034-5687(76)90045-1.

DOI:10.1016/0034-5687(76)90045-1

PMID:13472

Abstract

New mathematical formulas are presented to calculate directly the change in blood pH during CO2, and O2 exchange with blood. pH changes are calculated from changes in blood PCO2 and saturation values or from changes in blood PCO2 and blood PO2 values. Computational results agree well with information obtained from a Dill nomogram. These new formulas have applicability to the modelling of gas exchange in blood oxygenators as well as to estimating blood acid-base parameters following the mixing of blood samples.

摘要

本文提出了新的数学公式，用于直接计算血液在二氧化碳和氧气交换过程中的pH值变化。pH值变化可根据血液二氧化碳分压（PCO2）和饱和度值的变化来计算，也可根据血液PCO2和血氧分压（PO2）值的变化来计算。计算结果与从迪尔列线图获得的信息吻合良好。这些新公式适用于血液氧合器中气体交换的建模，以及估计血液样本混合后的酸碱参数。

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