蛋白质糖基化与微血管病变。
Glycosylation of proteins and microangiopathy.
作者信息
Brownlee M
机构信息
Albert Einstein College of Medicine, Bronx, New York.
出版信息
Hosp Pract (Off Ed). 1992 Feb;27 Suppl 1:46-50.
PMID:1347540
Abstract
Diabetic complications may result from chronic glycosylation of protein within cells and in the extracellular matrix. Prevention of glycosylation with aminoguanidine has forestalled complications in experimental diabetes.
摘要
糖尿病并发症可能源于细胞内及细胞外基质中蛋白质的慢性糖基化。用氨基胍预防糖基化已在实验性糖尿病中延缓了并发症的发生。
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