Desgranges C, Larrue J, Razaka G, Aumailley M, Bricaud H
C R Seances Soc Biol Fil. 1976;170(2):345-9.
Cell cultures of foetal rabbit aorta are cultivated with a lathyric agent (beta-amino-propio-nitrile) or with an hypercholesterolemic serum; if morphological features, in these two cases, correspond with modifications observed, in vivo, when adult rabbits are respectively submitted to the same treatment, enzymatic activities of collagen metabolism vary in opposite way. Therefore, the influence of different parameters to be studied on vascular cell functions become easier.
用致跛行剂(β-氨基丙腈)或高胆固醇血清培养胎兔主动脉细胞;如果在这两种情况下的形态学特征与成年兔分别接受相同处理时在体内观察到的改变相对应,那么胶原代谢的酶活性则会呈相反变化。因此,研究不同参数对血管细胞功能的影响变得更加容易。