Boismare F, Le Poncin M, Hacpille L
C R Seances Soc Biol Fil. 1976;170(2):455-9.
Analysis of hemodynamic parameters in untreated and treated dogs (levomepromazine 5 mg/kg i.v.) during supine and erect position showed, 1) that the regulation of cerebral blood flow remained in the anaesthetized (pentobarbital 25 mg/kg i.v.) dogs ; 2) that the sympathetic reaction induced different effects in various vascular regions ; 3) that levomepromazine induced an impairement of the mechanisms involved in the regulation of the encephalic irrigation.
对未治疗和接受治疗(静脉注射5 mg/kg左美丙嗪)的犬在仰卧位和直立位时的血流动力学参数进行分析显示:1)在麻醉(静脉注射25 mg/kg戊巴比妥)的犬中,脑血流调节仍然存在;2)交感神经反应在不同血管区域产生不同影响;3)左美丙嗪导致参与脑灌注调节的机制受损。