[内源性前列腺素与大鼠对去甲肾上腺素敏感性的降低]

C R Seances Soc Biol Fil. 1976;170(2):482-5.

In the Rat, desensitization to noradrenaline induced by perfusion of large doses of noradrenaline (0.5 to 0.75 mug/mn/100 g), is not suppressed by indomethacine (1 to 5 mg/100 g). Synthesis and release of endogenous prostaglandins of the PGE group are not the cause of the desensitization.

在大鼠中，大剂量去甲肾上腺素（0.5至0.75微克/分钟/100克）灌注诱导的对去甲肾上腺素的脱敏作用，不会被消炎痛（1至5毫克/100克）抑制。PGE组内源性前列腺素的合成与释放不是脱敏作用的原因。