Schreyer H, Schwarz G, Kerl H
Rofo. 1976 Sep;125(3):232-42. doi: 10.1055/s-0029-1230452.
The morphological and haemodynamic findings in the vessels of the forearm and hand in 21 patients with progressive scleroderma are described. In these patients, brachial arteriograms have been carried out before instituting fibrinolytic therapy. Injections were carried out before and after intra-arterial Priscolin and the results were compared. Obliterative changes in the digital arteries are already present during the oedematous stage. Between the oedematous and advanced stages, there are vascular changes of progressive severity. In the sclerotic stage, the changes may be less marked, but more often consist of advanced obliterative vascular disease; this cannot be distinguished from the atrophic stage. The haemodynamics of the digital arteries can be influenced by Priscolin and this provides some information regarding the arterial side of the dermal micro-circulation. Even during the oedematous stage one can observe contrast stasis which is irreversible and not influenced by Priscolin.
本文描述了21例进行性系统性硬化症患者前臂和手部血管的形态学和血流动力学表现。这些患者在接受纤溶治疗前均进行了肱动脉造影。在动脉内注射妥拉唑啉前后分别进行造影，并对结果进行比较。指动脉的闭塞性改变在水肿期就已出现。在水肿期和晚期之间，血管改变逐渐加重。在硬化期，改变可能不太明显，但更常见的是严重的闭塞性血管疾病；这与萎缩期难以区分。妥拉唑啉可影响指动脉的血流动力学，这为皮肤微循环的动脉侧提供了一些信息。即使在水肿期，也可观察到造影剂停滞，这是不可逆的，且不受妥拉唑啉影响。
