Pharmacokinetics of dipipanone after a single oral dose.
作者信息
Paterson S
机构信息
Department Forensic Medicine and Toxicology, Charing Cross and Westminster Medical School, London.
出版信息
Br J Clin Pharmacol. 1992 Apr;33(4):449-50. doi: 10.1111/j.1365-2125.1992.tb04066.x.
Abstract
A single oral dose of Diconal (dipipanone HCl 10 mg, cyclizine HCl 30 mg) was given to six volunteers. The mean peak plasma dipipanone concentration was 29 ng ml-1, the time to peak plasma concentration was 1-2 h, the mean elimination half-life was 3.5 h and the mean AUC was 156 ng ml-1 min. Less than 1% of the dose was excreted in urine unchanged over 24 h.
摘要
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本文引用的文献
1
Measurement of dipipanone using capillary gas chromatography.使用毛细管气相色谱法测定二醋吗啡。
J Chromatogr. 1988 Jan 22;424(1):152-7. doi: 10.1016/s0378-4347(00)81087-7.
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