[Metabolism of isonicotinic acid hydrazide and its derivatives in macroorganisms. IV. Demonstration of isonicotinyl hydrazones of pyruvic acid and alpha-ketoglutaric acid].
作者信息
IWAINSKY H
出版信息
Arzneimittelforschung. 1957 Dec;7(12):745-7.
PMID:13499151
Abstract
摘要
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Identification of isonicotinoylhydrazones of pyruvic and alpha-ketoglutaric acid in rat urine after treatment with isonicotinic acid hydrazide (isoniazid).在用异烟肼（异烟酰肼）处理大鼠后，对其尿液中丙酮酸和α-酮戊二酸异烟酰腙的鉴定。
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Low circulating levels of acid-labile hydrazones after oral administration of isonicotinic acid hydrazide.口服异烟肼后循环中酸不稳定腙水平较低。
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Identification of hydrazone of norethindrone, a metabolic product resulting from the interaction between isoniazid and norethindrone.炔诺酮腙的鉴定，一种异烟肼与炔诺酮相互作用产生的代谢产物。
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[The effect of isoniazid on glucide metabolism. III. The relation between the pyruvic acid and alpha-ketoglutaric acid concentrations in the rat liver and the level of isoniazid administration. The influence of the age of the experimental animal on the isoniazid effect].异烟肼对糖代谢的影响。III. 大鼠肝脏中丙酮酸和α-酮戊二酸浓度与异烟肼给药水平的关系。实验动物年龄对异烟肼作用的影响
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