Singh R K, Gambhir S S
Department of Pharmacology, Banaras Hindu University, Varanasi.
Indian J Physiol Pharmacol. 1992 Jan;36(1):65-9.
Vascular autonomic receptors in amphibians exhibit difference from more evolved mammalian species. Vascular perfusion studies in frog indicate constrictions by prominent muscarinic but rudimentary nicotinic constrictive regulation by cholinergic systems. Difference from classical effect-patterns of pharmacological interventions, observed in the study, make room to visualise complexity of additional regulatory mechanisms.
两栖动物的血管自主受体与进化程度更高的哺乳动物物种存在差异。对青蛙进行的血管灌注研究表明,胆碱能系统对血管有显著的毒蕈碱样收缩作用,但烟碱样收缩调节作用较弱。该研究中观察到的与药理学干预经典效应模式的差异,为设想其他调节机制的复杂性提供了空间。