抗炎药物在过敏性疾病治疗中的应用。

Anti-inflammatory drugs in the treatment of allergic disease.

作者信息

Szefler S J

机构信息

Department of Pediatrics, University of Colorado Health Sciences Center, Denver.

出版信息

Med Clin North Am. 1992 Jul;76(4):953-75. doi: 10.1016/s0025-7125(16)30334-0.

DOI:10.1016/s0025-7125(16)30334-0

PMID:1351972

Abstract

The treatment of asthma is undergoing significant change with an emphasis on anti-inflammatory therapy. While glucocorticoids are the most potent anti-inflammatory agent, certain patients fail to respond. These patients may be candidates for alternative anti-inflammatory therapy, such as troleandomycin, methotrexate, gold, hydroxychloroquine, or dapsone. In addition, the application of immunomodulator therapy, such as intravenous gamma globulin or cyclosporine, may be useful.

摘要

哮喘的治疗正在经历重大变革，重点在于抗炎治疗。虽然糖皮质激素是最有效的抗炎药物，但某些患者对此并无反应。这些患者可能适合接受其他抗炎治疗，如醋竹桃霉素、甲氨蝶呤、金制剂、羟氯喹或氨苯砜。此外，免疫调节剂治疗，如静脉注射丙种球蛋白或环孢素，可能会有帮助。