Metabolism of drugs. XIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 5. Further studies on isolation, characterisation, and identification of biotransformation products of the drug excreted in the urine of rabbit.
作者信息
YOSHIMURA H
出版信息
Pharm Bull. 1957 Dec;5(6):561-4. doi: 10.1248/cpb1953.5.561.
PMID:13527140
Abstract
摘要
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1
Metabolism of drugs. XIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 5. Further studies on isolation, characterisation, and identification of biotransformation products of the drug excreted in the urine of rabbit.药物代谢。十三。甲基己巴比妥（5-环己烯基-3,5-二甲基巴比妥酸）的代谢命运。5. 关于从兔尿中排泄的该药物生物转化产物的分离、表征和鉴定的进一步研究。
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2
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Metabolism of drugs. XVIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5 dimethylbarbituric acid). 8. The quantitative determination of main biotransformation products of methylhexabital in the urine of rabbits by ultra-violet spectrophotometry.药物代谢。十八。甲基己巴比妥（5-环己烯基-3,5-二甲基巴比妥酸）的代谢命运。8. 用紫外分光光度法对兔尿中甲基己巴比妥主要生物转化产物的定量测定。
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6
Metabolism of drugs. VIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3, 5-dimethylbarbituric acid). 4. Ultraviolet and infrared absorption spectra of the metabolites of MHB and related compounds.药物代谢。VIII. 甲基己巴比妥（5-环己烯基-3,5-二甲基巴比妥酸）的代谢命运。4. 甲基己巴比妥及其相关化合物代谢产物的紫外和红外吸收光谱。
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Hexobarbital metabolism: a new metabolic pathway to produce 1,5-dimethylbarbituric acid and cyclohexenone-glutathione adduct via 3'-oxohexobarbital.己巴比妥代谢：通过3'-氧代己巴比妥产生1,5-二甲基巴比妥酸和环己烯酮-谷胱甘肽加合物的新代谢途径。
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Metabolism of drugs. XXXI. Metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 10. Enzymatic oxidation of methylhexabital.药物代谢。三十一。甲基己巴比妥（5-环己烯基-3,5-二甲基巴比妥酸）的代谢命运。10. 甲基己巴比妥的酶促氧化
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