骨髓瘤中的红细胞酶。

Erythrocyte enzymes in myelomatosis.

作者信息

Hansen O P, Hanel H K

出版信息

Scand J Haematol. 1976 Sep;17(3):179-82. doi: 10.1111/j.1600-0609.1976.tb01173.x.

DOI:10.1111/j.1600-0609.1976.tb01173.x

Abstract

The activity of the erythrocyte enzymes: glucose-6-phosphate dehydrogenase, pyruvate kinase, glutathion reductase and ATPase were measured in 8 patients with untreated myelomatosis. Glucose-6-phosphate dehydrogenase was significantly increased. Glucose-6-phosphate dehydrogenase values were negatively correlated with the glomerular filtration rate as measured by 51Cr-EDTA clearance. The results support the existence of a shortened red cell survival in peripheral blood related to the degree of renal insufficiency.

摘要

在8例未经治疗的骨髓瘤患者中测定了红细胞酶的活性：葡萄糖-6-磷酸脱氢酶、丙酮酸激酶、谷胱甘肽还原酶和ATP酶。葡萄糖-6-磷酸脱氢酶显著升高。葡萄糖-6-磷酸脱氢酶的值与用51Cr-EDTA清除率测定的肾小球滤过率呈负相关。结果支持外周血中红细胞存活时间缩短与肾功能不全程度有关。